The meteoric rise of Ozempic as a weight-loss aid has been accompanied by a growing list of side effects—one of the most surprising being what's now referred to as “Ozempic teeth.” But what does this term actually mean, and should users be concerned?

Originally developed as a treatment for type 2 diabetes, Ozempic—along with similar GLP-1 receptor agonists like Wegovy and Mounjaro—has gained worldwide popularity for its ability to support weight loss. In fact, around 5% of UK residents reportedly used these types of injections last year.

These drugs work by mimicking a natural hormone that helps regulate blood sugar levels and slows down digestion, leading to reduced appetite and weight loss. However, as with many medications, they come with potential side effects. In rare cases, users have reported serious outcomes like hypoglycemia or even coma. Now, dental professionals are raising concerns about a different but increasingly common issue: "Ozempic teeth."

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What Is “Ozempic Teeth”?

The term “Ozempic teeth” isn’t a clinical diagnosis, but rather an emerging phrase used to describe a range of dental problems seen in some users of Ozempic and similar medications. These issues may include:

• Tooth decay

• Gum disease

• Bad breath

• Dry mouth

According to Dr. Sandip Sachar, a general and cosmetic dentist, his practice has observed a notable rise in dental issues among patients using semaglutide-based medications like Ozempic. While direct scientific proof is still lacking, real-world observations are drawing attention to a potential link.

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Why Might Ozempic Affect Your Teeth?

One likely explanation lies in saliva production. Experts believe that Ozempic can reduce saliva flow, leading to dry mouth—a condition that allows harmful bacteria to flourish and decreases the natural cleansing action that protects teeth and gums.

Additionally, nausea and vomiting, another known side effect of Ozempic, may expose teeth to stomach acid, damaging enamel and increasing the risk of cavities.

Dr. Daniel Atkinson, clinical lead at Treated.com, further notes that while “Ozempic teeth” isn't listed among the drug’s official side effects, indirect factors like acid reflux, dehydration, and nutritional deficiencies might be to blame.

“One possible explanation is that Ozempic can increase acid reflux,” Dr. Atkinson explained. “Over time, the extra acid may contribute to enamel erosion. Dehydration and a lack of key nutrients—common in calorie-restricted diets—can also compromise oral health.”

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Should You Be Worried?

Although the idea of developing “Ozempic teeth” may sound alarming, experts emphasize that basic oral care practices can go a long way in minimizing the risk.

Here are some simple tips for users:

• Stay hydrated: Sip water throughout the day to combat dry mouth.

• Brush after meals: Especially important if nausea or acid reflux occurs.

• Visit your dentist regularly: Early intervention can prevent minor issues from becoming serious.

• Maintain a balanced diet: Ensure you’re getting enough calcium, vitamin D, and other tooth-supporting nutrients.

While these dental issues aren't yet fully understood, increased awareness and proactive oral care can help users enjoy the benefits of weight loss injections without sacrificing their smile.